EBOO stands for Extracorporeal Blood Oxygenation and Ozonation, which is a lot of syllables for a fairly simple idea: your blood leaves your body through one IV line, passes through a closed, sterile filtration circuit where it's oxygenated and exposed to medical-grade ozone, and returns through a second IV line, cleaner and more oxygenated than it left. It's one of the most advanced therapies we offer, and like procaine neural therapy, it works best as a series rather than a single visit. Here's how it actually works, why we use two different filters across that series, and what it costs.
What EBOO Actually Is
A typical session treats roughly 2 liters of your blood over about 45 to 60 minutes. That's meaningfully more blood volume, treated more thoroughly, than older "10-pass" ozone autohemotherapy methods, because the blood is continuously filtered and oxygenated throughout the session rather than mixed with ozone gas in a single batch. Research on the process shows measurable biochemical changes immediately after treatment, including a several-fold increase in markers of controlled oxidative activity, without meaningful damage to red blood cells when done correctly. That controlled, temporary oxidative signal is the point: it's what triggers the body's own adaptive response.
At low, medically controlled doses, ozone doesn't just "kill germs" the way people sometimes assume. It creates a brief, measured stress signal that prompts your body to upregulate its own antioxidant enzymes (things like superoxide dismutase and glutathione), a pattern researchers call oxidative preconditioning or hormesis: a small, controlled stress that leaves the system more resilient afterward, similar in concept to how exercise creates temporary stress that leads to adaptation. Reviews of the evidence describe ozone therapy modulating inflammation by lowering inflammatory enzymes and raising anti-inflammatory mediators, which is the mechanism behind why it's used for systemic inflammation and immune support, not just as a novelty treatment.
Why We Use Two Different Filters
This is the part that surprises people: we don't run the same filter every session. Our standard EBOO filter is designed to prime the process, oxygenating and ozonating your blood in a way that mobilizes what your body needs to clear and gets your systems ready to detox. Our advanced filter, EBOO Plus, is built to carry that further: a more thorough filtration pass that does the heavier lifting of the detox itself. Running the standard filter first and the advanced filter later in the series isn't arbitrary; it's the same logic as prepping soil before you plant. You get more out of the deeper filtration when the groundwork has already been laid.
Who May Benefit
People typically seek out EBOO for:
- Systemic inflammation or an immune system that feels like it's constantly playing catch-up
- Chronic fatigue that hasn't responded to more conservative approaches
- Support during detox-focused protocols, alongside diet and lifestyle changes, not as a replacement for them
- Recovery support for people managing complex, longstanding health conditions
- General cellular health and healing support, especially for people who've already addressed the basics (sleep, diet, movement) and are looking for the next layer
We'll say the same thing here we'd say about any advanced therapy: EBOO is a well-reasoned, physiologically grounded treatment with real research behind the ozone mechanism itself, but it isn't a cure-all, and results vary by person. It works best as part of a broader plan, not a standalone fix.
Why It's a Series, Not a Single Treatment
One EBOO session gives your body a single, isolated push. A series gives it a pattern to build on, which matters because the hormetic, adaptive response the therapy relies on tends to compound with repeated, appropriately spaced exposure rather than happening all at once. Our standard series is 3 treatments: 2 sessions with the standard EBOO filter to prime the process, followed by 1 session with the advanced EBOO Plus filter to complete it.
EBOO (standard filtration): $900 per session
EBOO Plus (advanced filtration): $1,100 per session
Series of 3 (2 EBOO + 1 EBOO Plus): $2,800 (a $100 savings versus booking each session individually)
As with our other advanced therapies, EBOO starts with a consultation, not an order form. It involves an extracorporeal blood circuit and real oxidative exposure, so we review your health history first; G6PD deficiency, pregnancy, uncontrolled hyperthyroidism, active bleeding disorders, and severe cardiovascular instability are all reasons EBOO may not be appropriate, which is exactly why this isn't something to self-select into off a price list.
What to Expect
Most people describe the session itself as easy: you're reclined and resting for the better part of an hour while the circuit does its work, similar to a lengthy IV appointment. Reported effects afterward tend to build across the series rather than hit all at once: more consistent energy, less of that "inflamed everywhere" feeling, and a sense of recovering faster from the normal wear of daily life. As always, we'd rather describe that honestly as a pattern people report than promise it as a guarantee.
If systemic inflammation, stubborn fatigue, or a body that feels like it's playing catch-up sounds familiar, book a consultation and let's talk through whether an EBOO series fits into your plan.
Sources
- Extracorporeal Blood Oxygenation and Ozonation: Clinical and Biological Implications of Ozone Therapy (PubMed)
- Extracorporeal Blood Oxygenation and Ozonation (EBOO) (PubMed)
- Ozone Oxidative Preconditioning: A Protection Against Cellular Damage by Free Radicals (Mediators of Inflammation)
- Effect of Ozone Therapy on Oxidative Stress Indices in Chronic Inflammatory Diseases: A Systematic Review and Meta-Analysis (ScienceDirect)
- Medical Ozone: Mechanisms, Biological Effects and Clinical Evidence, A Narrative Review (Frontiers in Medicine)
- Safety & Contraindications (EBOO + Ozone Therapy)